Banedif Ointment

Therapeutic Class

Antibacterials, Topical

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Ointment (NRN: 04-2046): Neomycin sulphate 5mg, Zinc bacitracin 500 IU per g.

Pack size: Collapsible tube of 20g.

Powder (NRN: 04-1271): Neomycin sulphate 5mg, Zinc bacitracin 250 IU per g.

Pack size: Plastic bottle of 5g.

Pharmacology

An external preparation containing a mixture of aminoglycoside (Neomycin Sulphate) and a polypeptide antibiotic (Zinc Bacitracin) as active constituents.

Bacitracin: Interferes with bacterial cell wall synthesis by inhibiting regeneration of phospholipid receptors involved with peptidoglycan synthesis.

Neomycin: Inhibits protein synthesis by binding to ribosomal RNA, causing bacterial genetic code misreading.

Indications

Bacterial infections of the skin and soft tissue infections including impetigo, folliculitis, furunculosis, erythrema, gangrenosum, necrotising soft tissues infections, ulcerating skin infections, burns, anthrax, acne and rosacea.

Contra-indications

Hypersensitivity to any of the components of Banedif.

Precautions/Warnings

Banedif should not be used on a large area of open wound.

Interactions

Interactions involving Banedif have not been well documented. However, like other medicines, consult with your healthcare professional before use.

Adverse Effects

Not very common, it may cause skin sensitization

Dosage & Administration

Apply sufficiently to the affected area 3-4 times daily or as directed by the Physician.

Storage/Handling Recommendations

Keep your medicine in a cool, dry place.